A learning health system approach to the COVID-19 pandemic: System-wide changes in clinical practice and 30-day mortality among hospitalized patients.
Erin K McCrearyKevin E KipJ Ryan BariolaMark SchmidhoferTami MinnierKatelyn MayakDebbie AlbinJessica DaleyKelsey LinstrumErik HernandezRachel SackrowitzKailey HughesChristopher HorvatGraham M SnyderBryan J McVerryDonald M YealyDavid T HuangDerek C AngusOscar C MarroquinPublished in: Learning health systems (2022)
In our large LHS, near real-time changes in clinical management of COVID-19 patients happened promptly as scientific publications and regulatory approvals occurred throughout the pandemic. Alongside these changes, patients with COVID-19 experienced lower adjusted 30-day mortality following hospital admission over time.