Trimodality Therapy vs Definitive Chemoradiation in Older Adults With Locally Advanced Esophageal Cancer.
Charles E GaberNicholas J ShaheenJessie K EdwardsRobert S SandlerHazel B NicholsHanna K SanoffJennifer L LundPublished in: JNCI cancer spectrum (2022)
Compared with definitive chemoradiation, trimodality therapy was associated with reduced mortality but increased risk of function-related adverse events. Discussing these tradeoffs may help optimize care plans.
Keyphrases
- locally advanced
- rectal cancer
- neoadjuvant chemotherapy
- squamous cell carcinoma
- radiation therapy
- phase ii study
- healthcare
- palliative care
- physical activity
- stem cells
- cardiovascular events
- risk factors
- quality improvement
- cardiovascular disease
- type diabetes
- mesenchymal stem cells
- coronary artery disease
- community dwelling
- pain management
- muscle invasive bladder cancer
- cell therapy