Reduced plasma concentrations of transforming growth factor beta1 (TGF-beta1) in obese women.

F CoricaA AllegraM BuemiA CorsonelloS BonanzingaF RubinoL CastagnaD Ceruso

Published in: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity (2005)

The reduction in TGF-beta1, an antilipogenic factor, may play a role in the pathogenesis of obesity and could be involved in the development of some obesity-related endocrine alterations.

Keyphrases

transforming growth factor
weight loss
epithelial mesenchymal transition
metabolic syndrome
insulin resistance
type diabetes
weight gain
high fat diet induced
bariatric surgery
adipose tissue
signaling pathway
obese patients
body mass index
physical activity
skeletal muscle