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High-affinity ZnT8 Autoantibodies by Electrochemiluminescence Assay Improve Risk Prediction for Type 1 Diabetes.

Xiaofan JiaLing HeDongmei MiaoKathleen WaughCristy Geno RasmussenFran DongAndrea K SteckMarian RewersLiping Yu
Published in: The Journal of clinical endocrinology and metabolism (2021)
A large proportion of ZnT8A by RBA are single ZnT8A with low T1D risk, whereas ZnT8A by ECL was of high affinity and high prediction for T1D development.
Keyphrases
  • type diabetes
  • systemic lupus erythematosus
  • cardiovascular disease
  • insulin resistance
  • metabolic syndrome
  • adipose tissue
  • skeletal muscle
  • single cell