Gold(I)-Initiated Cycloisomerization/Diels-Alder/Retro-Diels-Alder Cascade Strategy to Biaryls.

Shengfei JinYujie NiuChengjun LiuLifeng ZhuYangming LiShanshan CuiZhiling XiongMaosheng ChengBin LinYong-Xiang Liu

Published in: The Journal of organic chemistry (2017)

A unique approach to biaryls was developed on the basis of propargyl vinyl ethers and dienophiles substrates via a gold(I)-initiated cycloisomerization/Diels-Alder/retro-Diels-Alder cascade reaction. The scope and mechanism of the reaction were investigated on the basis of a series of synthetic substrates, control experiments, and DFT calculations.

Keyphrases

density functional theory
molecular dynamics simulations
atomic force microscopy
electron transfer
high speed