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[Hypothalamic hamartoma dissection using focused ultrasound under MRI control. The first successful experience in Russia].

R M GalimovaSergey Nikolaevich IllarioshkinShamil SafinIgor Vyacheslavovich BuzaevD I NabiullinaD K KrekotinS R NurmukhametovaYu A SidorovaG N AkhmadeevaF F KashapovT Z YakupovD R Teregulova
Published in: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko (2024)
Treatment of motor disorders by MRI-guided focused ultrasound is an alternative to neuro- and radiosurgery such as stereotactic radiofrequency ablation and thalamotomy with a gamma knife. However, safety, efficacy and feasibility of this technology for intracranial neoplasms are still unclear. The authors report successful hypothalamic hamartoma dissection by MRI-guided focused ultrasound in a 32-year-old woman with drug-resistant gelastic epilepsy and violent laughter and crying attacks. Magnetic resonance imaging revealed type II hypothalamic hamartoma. The last one was detached from surrounding brain tissue by MRI-guided focused ultrasound without side effects. Symptoms regressed immediately after surgery. No laughter and crying attacks were observed throughout 6-month follow-up.
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