Bu-Zhong-Yi-Qi Granule Enhances Colonic Tight Junction Integrity via TLR4/NF-κB/MLCK Signaling Pathway in Ulcerative Colitis Rats.

Xiuhong Kang Mengdi Jia Luqing Zhao Shengsheng Zhang

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

The therapeutic effect of BZYQ on UC is at least partially through regulation of the secretion of some inflammatory cytokines and improvement of TJ integrity via TLR4/NF-κB/MLCK pathway.

Keyphrases

signaling pathway
ulcerative colitis
pi k akt
toll like receptor
inflammatory response
nuclear factor
lps induced
immune response
epithelial mesenchymal transition
induced apoptosis
blood brain barrier
cell proliferation