Different Expressions of Specific Transcription Factors of Th1 (T-bet) and Th2 cells (GATA-3) by Peripheral Blood Mononuclear Cells From Patients With Multiple Sclerosis.

Zahra EtesamMaryam NematiMohammad-Amin EbrahimizadehHossain-Ali EbrahimiHossain HajghaniTahereh KhaliliAbdollah Jafarzadeh

Published in: Basic and clinical neuroscience (2018)

These results probably indicate an imbalance in Th1/Th2 cells in the level of transcription factors with a tendency toward Th1 cells in MS. The clinical utilization of the transcription factors as novel biomarkers of MS should be evaluated in further studies.

Keyphrases

transcription factor
induced apoptosis
cell cycle arrest
mass spectrometry
multiple sclerosis
ms ms
cell death
signaling pathway
pi k akt