Diagnosis and Management of Posterior Cortical Atrophy.
Keir X X YongJonathan Graff-RadfordSamrah AhmedMarianne ChapleauRik OssenkoppeleDeepti PutchaGil D RabinoviciAida Suarez-GonzalezJonathan M SchottSebastian CrutchEmma HardingPublished in: Current treatment options in neurology (2023)
PCA diagnosis is frequently delayed, and people are likely to receive misdiagnoses of ocular or psychological conditions. Current treatment of PCA is symptomatic - pharmacological and non-pharmacological - and the use of most treatment options is based on small studies or expert opinion. Recommendations for non-pharmacological approaches include interdisciplinary management tailored to the PCA clinical profile - visual-spatial - rather than memory-led, predominantly young onset - and psychosocial implications. Whilst emerging disease-modifying treatments have not been tested in PCA, an accurate and timely diagnosis of PCA and determining underlying pathology is of increasing importance in the advent of disease-modifying therapies for AD and other albeit rare causes of PCA.