Total coumarins of Pileostegia tomentella induces cell death in SCLC by reprogramming metabolic patterns, possibly through attenuating β-catenin/AMPK/SIRT1.

Ying LiuKun WuJie YangFucui ZhuLi WangHua SuYing LiLu LuGuoshou LuXiaoxi Hu

Published in: Chinese medicine (2023)

Our results demonstrated TCPT induces cell death of SCLC by reprograming metabolic patterns, possibly through attenuating master metabolic pathway axis β-catenin/AMPK/SIRT1.

Keyphrases

cell death
epithelial mesenchymal transition
cell proliferation
oxidative stress
skeletal muscle
cell cycle arrest
ischemia reperfusion injury
protein kinase
signaling pathway