Peanut components measured by ISAC: comparison with ImmunoCap and clinical relevance in peanut allergic children.
H K BrandM W J SchreursJ A M EmonsR Gerth van WijkH de GrootN J T ArendsPublished in: Clinical and molecular allergy : CMA (2021)
Ara h 6 and Ara h 2 sIgE in multiplex ISAC are both good predictors of clinical peanut allergy in Dutch children, and their performance is comparable to the use of Ara h 2 in singleplex FEIA. The simultaneous measurement of different peanut components using ISAC is an advantage and clinically useful to detect peanut allergic children that are Ara h 2 negative but sensitized to other peanut proteins such as Ara h 6.