Enhanced nuclear localization of phosphorylated MLKL predicts adverse events in patients with dilated cardiomyopathy.

Yugo FujitaToshiyuki YanoHiromitsu KanamoriDaigo NagaharaAtsuko MuranakaHidemichi KouzuAtsushi MochizukiMasayuki KoyamaNobutaka NaganoTakefumi FujitoRyo NishikawaNaoyuki KamiyamaMarenao TanakaAtsushi KunoMasaya TannoTetsuji Miura

Published in: ESC heart failure (2022)

The results suggest that increased localization of nuclear p-MLKL in cardiomyocytes is associated with left ventricular diastolic dysfunction and future adverse events in DCM.

Keyphrases

left ventricular
hypertrophic cardiomyopathy
heart failure
acute myocardial infarction
cardiac resynchronization therapy
aortic stenosis
blood pressure
mitral valve
oxidative stress
left atrial
current status
atrial fibrillation