Intravenous injection of mesenchymal stem cell spheroids improves the pulmonary delivery and prolongs in vivo survival.

Yoshihiko ShimazawaKosuke Kusamori Kazunori ShimizuAsuka ShimomuraRyo TakasakiYukiya TakayamaKazunori ShimizuSatoshi KonishiMakiya Nishikawa

Published in: Biotechnology journal (2021)

These results indicate that spheroid formation improved the pulmonary delivery and survival of MSCs, as well as their therapeutic potential against inflammatory pulmonary diseases.

Keyphrases

pulmonary hypertension
mesenchymal stem cells
free survival
high dose
low dose
ultrasound guided
cell therapy