Electroencephalogram and heart rate variability features as predictors of responsiveness to vagus nerve stimulation in patients with epilepsy: a systematic review.

Sarosh Irfan MadhaniMehdi AbbasiYang LiuJorge Arturo LarcoEvan NicolaiGregory WorrellLuis Savastano

Published in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2022)

HRV parameters and EEG characteristics including focal seizures and P300 wave have been reported as potential biomarkers for VNS outcomes in people with medically refractive epilepsy. However, the contradictory findings imply a need for validation through clinical trials.

Keyphrases

heart rate variability
clinical trial
heart rate
temporal lobe epilepsy
functional connectivity
working memory
resting state
blood pressure
type diabetes
metabolic syndrome
phase ii
open label
glycemic control
phase iii
placebo controlled