Near complete remission of an inoperable pancreatic acinar cell carcinoma after BRAF-/MEK-inhibitor treatment-A case report and review of the literature.

Lennart von Fritsch Nikolas von BubnoffKlaus WeberJutta KirfelCleopatra SchreiberTobias KeckUlrich Wellner

Published in: Genes, chromosomes & cancer (2024)

Studies suggest that up to one-fourth of PACCs carry a BRAF mutation and might therefore be susceptible to a BRAF-/MEK-inhibitor therapy. This offers a new therapeutic pathway to treat this rare but malignant neoplasm.

Keyphrases

metastatic colorectal cancer
wild type
low grade
stem cells
radiation therapy
rheumatoid arthritis
locally advanced
bone marrow
ulcerative colitis
signaling pathway