Chronic alcohol induced mechanical allodynia by promoting neuroinflammation: a mouse model of alcohol-evoked neuropathic pain.
Vittoria BorgonettiAmanda J RobertsMichal BajoNicoletta GaleottiMarisa RobertoPublished in: British journal of pharmacology (2023)
We showed that the CIE-2BC model induces two distinct pain conditions specific to the type of ethanol exposure: abstinence-related hypersensitivity in dependent mice and alcohol-evoked neuropathic pain in about a half of the non-dependent mice.
Keyphrases
- neuropathic pain
- spinal cord
- spinal cord injury
- mouse model
- drug induced
- alcohol consumption
- high fat diet induced
- traumatic brain injury
- high glucose
- type diabetes
- cognitive impairment
- adipose tissue
- smoking cessation
- diabetic rats
- chronic pain
- lipopolysaccharide induced
- pain management
- endothelial cells
- lps induced
- metabolic syndrome
- inflammatory response