Humoral response to SARS-CoV-2 infection among liver transplant recipients.
Chiara BecchettiAnnelotte G C BroekhovenGéraldine DahlqvistMontserrat FragaMarco Fabrizio ZambelliOlga CiccarelliAnne-Catherine SaouliArianna TrizzinoVanessa BanzJean-François DufourAnna H E RoukensShessy P Torres MoralesSebenzile K MyeniMarjolein KikkertMariet C W FeltkampMinneke J CoenraadPublished in: Gut (2022)
Our findings suggest that the humoral response of LT recipients is only slightly lower than expected, compared with COVID-19 immunocompetent controls. Testing for anti-S antibodies alone can lead to an overestimation of the neutralising ability in LT recipients. Altogether, routine antibody testing against separate SARS-CoV-2 antigens and functional testing show that the far majority of LT patients are capable of mounting an adequate antibody response with neutralising ability.