Lack of association between proton pump inhibitor use and decline in cognitive performance in the ELSA-Brasil cohort.
Andrêza Soares Dos SantosSara Teles de MenezesIsabela M BensenorAlessandra Carvalho GoulartSandhi Maria BarretoRoberta Carvalho de FigueiredoPublished in: European journal of clinical pharmacology (2021)
In this cohort middle-aged and elderly adults, after average interval of 3.9 years (relatively short time to detect cognitive decline in a young cohort), the use and time of use of PPIs at the beginning of the study were not associated with a decline in cognitive performance in these tests between visits.