Exogenous interleukin-1 beta promotes the proliferation and migration of HeLa cells via the MEK/ERK signaling pathway.
Jiajia ZhangLei WangYiying LiuWei LiuZhenling MaPublished in: Molecular biology reports (2022)
Our data suggest that exogenous IL-1β regulates HeLa cell functions by regulating the MEK/ERK signaling pathway and by targeting JUN, RELB, and NF-κB2. Our study uncovered a potential association across IL-1β, cervical tumor development, and cancer progression.
Keyphrases
- pi k akt
- cell cycle arrest
- signaling pathway
- induced apoptosis
- cell proliferation
- epithelial mesenchymal transition
- papillary thyroid
- single cell
- squamous cell
- machine learning
- squamous cell carcinoma
- oxidative stress
- risk assessment
- climate change
- young adults
- deep learning
- endoplasmic reticulum stress
- human health
- artificial intelligence
- toll like receptor