Apocynin Attenuates Acute Kidney Injury and Inflammation in Rats with Acute Hypertriglyceridemic Pancreatitis.

Xiaojia YangKailiang ZhaoWenhong DengLiang ZhaoHongzhong JinFangchao MeiYu ZhouMan LiWei Xing Wang

Published in: Digestive diseases and sciences (2019)

NOX may play an important role in HTGP-associated kidney injury through Akt/GSK-3β pathway. Apocynin can significantly downregulate the level of NOX and play a protective role in HTGP-related kidney injury through Akt/GSK-3β pathway.

Keyphrases

signaling pathway
acute kidney injury
pi k akt
cell proliferation
liver failure
reactive oxygen species
cardiac surgery
drug induced
respiratory failure
intensive care unit
aortic dissection
mechanical ventilation