Sarcoid-resembling granulomatous lung disease secondary to occupational magnetite iron dust exposure.
Lewis XiaoAnil KookanaRobert McClureSubash Shanthakumar HeraganahallyPublished in: Respirology case reports (2018)
Non-caseating granulomatous pulmonary conditions resembling sarcoidosis secondary to industrial/occupation exposure to magnetite iron ore dusts have been rarely documented in the literature. This is a case report of a 58-year-old blast crew member involved in iron ore/magnetite mining who presented with a 12-month history of chronic dry cough. High-resolution computed tomography revealed bilateral interstitial opacities. Lung biopsy demonstrated sarcoid-like granulomatous inflammation. Oral corticosteroid treatment improved the cough. Radiological features did not resolve despite treatment and yet remained stable following no subsequent exposure to iron mining dust.
Keyphrases
- computed tomography
- iron deficiency
- interstitial lung disease
- systematic review
- magnetic resonance imaging
- oxidative stress
- health risk
- single cell
- heavy metals
- positron emission tomography
- human health
- magnetic resonance
- climate change
- wastewater treatment
- risk assessment
- replacement therapy
- ultrasound guided
- smoking cessation