Pituitary-immune bidirectional crosstalk under systemic inflammation.

Published in: PLoS biology (2023)

The pituitary gland responds to and modulates immune stress through the hypothalamus-pituitary-adrenal axis. A new study in PLOS Biology reveals unconventional bidirectional communication between hormone-producing cells and the immune system upon systemic inflammation.

Keyphrases

growth hormone
induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
cell death
oxidative stress