The Nickel-Pincer Complex in Lactate Racemase Is an Electron Relay and Sink that acts through Proton-Coupled Electron Transfer.

Published in: Angewandte Chemie (International ed. in English) (2017)

QM/MM calculations reveal that the nickel pincer complex in lactate racemase functions as a reversible "single-center electrode" that accepts and donates back an electron. In this way, it catalyzes the isomerization process d-lactate⇌l-lactate through successive proton-coupled electron-transfer steps.

Keyphrases

electron transfer
carbon nanotubes
reduced graphene oxide
molecular dynamics simulations
molecular dynamics