On-target sorafenib toxicity predicts improved survival in hepatocellular carcinoma: a multi-centre, prospective study.

Jessica HowellD J PinatoR RamaswamiD BettingerT ArizumiC FerrariC YenA GibbinM E BurloneG GuaschinoL SellersJ BlackM PirisiM KudoR ThimmeJ-W ParkR Sharma

Published in: Alimentary pharmacology & therapeutics (2017)

Development of sorafenib-related toxicity including diarrhoea, hypertension and hand-foot syndrome is associated with prolonged overall survival in patients with advanced-stage HCC on sorafenib.

Keyphrases

oxidative stress
blood pressure
free survival
case report
oxide nanoparticles