M ycobacterium tuberculosis -specific CD4 T-cell scoring discriminates tuberculosis infection from disease.
Andrej ManteiTim MeyerMariana SchürmannChristiane BeßlerHarald BiasDavid KriegerTorsten BauerPetra BacherJohannes HelmuthHans-Dieter VolkDirk SchürmannAlexander ScheffoldChristian MeiselPublished in: The European respiratory journal (2022)
With low time requirement, ease of sample collection, and high sensitivity and specificity both for pulmonary and extrapulmonary TB disease, we believe this novel standardised TB-Flow Assay will improve the work-up of patients with suspected TB disease, supporting rapid TB diagnosis and facilitating treatment decisions.