Measuring Tuberculosis Medication Adherence: A Comparison of Multiple Approaches in Relation to Urine Isoniazid Metabolite Testing Within a Cohort Study in India.

Ramnath SubbaramanBeena E ThomasJ Vignesh KumarMaya Lubeck-SchrickerAmit KhandewaleWilliam ThiesMisha EliasziwKenneth H MayerJessica E Haberer

Published in: Open forum infectious diseases (2021)

Alternate measures missed detecting at least 30% of people who were nonadherent by urine testing. The last missed dose question performed similarly to 99DOTS using patient-reported doses alone. Tuberculosis programs should evaluate the feasibility of integrating more accurate, objective measures, such as urine testing, into routine care.

Keyphrases

mycobacterium tuberculosis
patient reported
healthcare
pulmonary tuberculosis
palliative care
hiv aids
high resolution
emergency department
mass spectrometry
hepatitis c virus
human immunodeficiency virus
fluorescent probe
hiv infected
antiretroviral therapy
drug induced