123I-FP-CIT striatal binding ratios do not decrease significantly with age in older adults.

Gemma RobertsJames J LloydGeorge S PetridesPaul C DonaghyJoseph P M KaneRory DurcanSarah LawleyKim HoweAndrew J SimsJohn-Paul TaylorJohn T O'BrienAlan J Thomas

Published in: Annals of nuclear medicine (2019)

We found no statistically significant age-related decline in SBR in adults over 60 years of age without Lewy body disease. Commercial software packages that apply a fixed rate of age correction may be overcorrecting for age in older adults, which could contribute to misdiagnosis.

Keyphrases

physical activity
binding protein