Deep Molecular and In Silico Protein Analysis of p53 Alteration in Myelodysplastic Neoplasia and Acute Myeloid Leukemia.
Kristóf MadarászJános András MótyánJudit BedekovicsZsófia MiltényiAnikó UjfalusiGábor MéhesAttila MokánszkiPublished in: Cells (2022)
These molecular and in silico protein data further support that MDS with increased-blast (MDS-IB) is an intermediate group between AML-MR and MDS with low-blast (MDS-LB) patients, which frequently progresses to AML and is therefore considered a pre-leukemic condition.
Keyphrases
- acute myeloid leukemia
- allogeneic hematopoietic stem cell transplantation
- end stage renal disease
- molecular docking
- ejection fraction
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- protein protein
- amino acid
- high grade
- bone marrow
- single molecule
- patient reported outcomes
- machine learning
- contrast enhanced