CD4 T lymphocyte subsets display heterogeneous susceptibility to apoptosis induced by serum from patients with systemic lupus erythematosus.

Fernanda Vieira MesquitaVanessa FerreiraDanilo MesquitaLuis Eduardo Coelho de Andrade

Published in: Advances in rheumatology (London, England) (2023)

Our findings indicate that the serum of patients with active SLE stimulates apoptosis of CD4 + T cells in general and exhibit differentiated effects on CD4 + T-cell subsets.

Keyphrases

peripheral blood
endoplasmic reticulum stress
oxidative stress
cell cycle arrest
cell death
systemic lupus erythematosus
disease activity
pi k akt