Multimodal profiling of chordoma immunity reveals distinct immune contextures.
Siddh van OostDebora M MeijerMarieke E IjsselsteijnJessica P RoelandsBrendy E M W van den AkkerRuud van der BreggenInge H Briaire-de BruijnManon van der PloegPauline M Wijers-KosterSamuel B PolakWilco C PeulRobert J P van der WalNoel F C C de MirandaJudith V M G BovéePublished in: Journal for immunotherapy of cancer (2024)
Our findings shed light on the natural immunity against chordomas through the identification of distinct immune contextures. Understanding their immune landscape could guide the development and application of immunotherapies in a tailored manner, ultimately leading to an improved clinical outcome for patients with chordoma.