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Effects of long-term lithium therapy on kidney functioning in mood disorders: A population-based historical cohort study.

Ajay K ParsaikAanchal ChaudharyShivy SharmaBrooke Ellen DelgoffeRachel GaborBalwinder Singh
Published in: Bipolar disorders (2024)
The findings suggest that CKD occurs in 15% of patients with mood disorder receiving LTLT, with its progression potentially influenced by existing comorbidities rather than lithium alone. These results underscore the importance of monitoring kidney function in patients on LTLT and considering individual risk factors for CKD development. In patients who developed CKD, Li discontinuation did not impact change in kidney function.
Keyphrases
  • chronic kidney disease
  • bipolar disorder
  • solid state
  • sleep quality
  • depressive symptoms
  • physical activity