Thioether-directed Rh(III)-catalyzed peri -selective acyloxylation of arenes.
Hui XieJia-Lin SongChun-Yong JiangYan-Xia HuangJun-Yi ZengXu-Ge LiuShang-Shi ZhangFan YangPublished in: Organic & biomolecular chemistry (2022)
A thioether directed acyloxylation of arenes has been realized via Cp*Rh(III)-catalyzed C-H activation and subsequent coupling with carboxylic acids. This new method showed high functional group compatibility and broad substrate scope. Primary mechanistic studies have been conducted and a tentative reaction mechanism was proposed. It represents the first example of a thioether-directed Cp*Rh(III)-catalyzed C(sp 2 )-H acyloxylation reaction.
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