Comprehensive Review of Topical Analgesics for Chronic Pain.
Jillian A MaloneyScott PewChristopher WieRuchir GuptaJohn FreemanNatalie StrandPublished in: Current pain and headache reports (2021)
Studies have found topical NSAIDs are useful in treating acute musculoskeletal pain syndromes (strains and sprains) and show some efficacy in treating hand and knee osteoarthritis (Derry et al. Cochrane Database Syst Rev 5:CD008609, 2017). Topical capsaicin 8% has been shown to be efficacious in the treatment of postherpetic neuralgia, painful diabetic peripheral neuropathy, and HIV-neuropathy (Derry et al. Cochrane Database Syst Rev 1:CD007393, 2017). Topical lidocaine has been widely studied and found to reduce pain in patients with postherpetic neuralgia (Knezevic et al. Pain Manag 7:537-58, 2017). Although many other topical analgesics are available, there is limited data to support the efficacy of other agents. Topical analgesics are a relatively benign treatment for chronic pain conditions including neuropathic pain, musculoskeletal, and myofascial pain. There is evidence to support the use of topical NSAIDs, high concentration topical capsaicin, and topical lidocaine for various painful conditions.
Keyphrases
- chronic pain
- neuropathic pain
- wound healing
- pain management
- knee osteoarthritis
- spinal cord
- spinal cord injury
- escherichia coli
- type diabetes
- postoperative pain
- antiretroviral therapy
- human immunodeficiency virus
- liver failure
- intensive care unit
- deep learning
- machine learning
- big data
- extracorporeal membrane oxygenation
- hiv testing
- replacement therapy
- hiv aids
- respiratory failure
- smoking cessation