SCD rs41290540 single-nucleotide polymorphism modifies miR-498 binding and is associated with a decreased risk of coronary artery disease.

Zhou LiuXiaojian YinHui MaiGuangning LiZhijun LinWanxin JieKanglan LiHaihong ZhouShouchao WeiLi HuWanjuan PengJiajing LinFeng YaoHua TaoXing-Dong XiongKeshen Li

Published in: Molecular genetics & genomic medicine (2020)

This study demonstrates that the SCD rs41290540 may be associated with a decreased risk of CAD, lower serum TC, and decreased miR-498 binding.

Keyphrases

coronary artery disease
cell proliferation
long non coding rna
long noncoding rna
cardiovascular events
binding protein
coronary artery bypass grafting
acute coronary syndrome
aortic valve
transcatheter aortic valve replacement
aortic stenosis