Comparative Study on the Pharmacokinetics of Paeoniflorin, White Peony Root Water Extract, and Taohong Siwu Decoction After Oral Administration in Rats.

Wei-Chun ChenXiao-Yi LiangLi-Yuan XieMing-An WuQi ShenLi-Mei YaoWei ZhaoShi-Jie ZhangQi WangYong LiangWei-Rong Li

Published in: European journal of drug metabolism and pharmacokinetics (2023)

A highly specific, sensitive, and rapid HPLC-MS-MS method was developed and applied for the determination of PF in rat plasma. It was found that TSD and WPR can prolong the action time of paeoniflorin in the body.

Keyphrases

ms ms
solid phase extraction
liquid chromatography tandem mass spectrometry
high performance liquid chromatography
oxidative stress
simultaneous determination
molecularly imprinted
anti inflammatory
mass spectrometry
quantum dots