Clinical characteristics and prognosis of patients with antiphospholipid antibodies based on cluster analysis: an 8-year cohort study.
Wanting QiJiuliang ZhaoCan HuangNan JiangJing LiChanyuan WuShangzhu ZhangChaojun HuDong XuQian WangMengtao LiXinping TianYan ZhaoXiao-Feng ZengPublished in: Arthritis research & therapy (2022)
We identified 4 clinical phenotypes of aPL-positive patients. Non-criteria manifestations may indicate underlying SLE, for which immunosuppressive therapy besides anticoagulation may be necessary. Patients with isolated LA positivity suffered similar risks with secondary APS and patients with multiple cardiovascular risk factors. Attention should be paid to male patients, and the screening of cardiovascular risk factors should never be ignored.
Keyphrases
- cardiovascular risk factors
- end stage renal disease
- ejection fraction
- newly diagnosed
- systemic lupus erythematosus
- cardiovascular disease
- metabolic syndrome
- peritoneal dialysis
- venous thromboembolism
- atrial fibrillation
- bone marrow
- patient reported outcomes
- rheumatoid arthritis
- working memory
- cell therapy
- chemotherapy induced