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Tryptophanyl-tRNA Synthetase Sensitizes Hormone Receptor-Positive Breast Cancer to Docetaxel-Based Chemotherapy.

Kyung-Min LeeEun Hye HwangSeong Eun KangCheng Hyun LeeHyebin LeeHyeon Jeong OhKwang-Soo KimJiwon KohHan-Suk Ryu
Published in: Journal of breast cancer (2020)
Our results suggest that WARS might be a potential predictor for chemotherapy response in patients with HR-positive breast cancer as well as a novel molecular target to improve chemosensitivity.
Keyphrases
  • positive breast cancer
  • locally advanced
  • rectal cancer
  • squamous cell carcinoma
  • radiation therapy
  • induced apoptosis
  • single molecule
  • oxidative stress
  • endoplasmic reticulum stress