Deciphering the genetic architecture of atrial fibrillation offers insights into disease prediction, pathophysiology and downstream sequelae.

Qiqiang HeYuying LiLijuan WangFengzhe XuTherese Hesketh Michael G LevinYing XiongBenjamin F VoightScott M DamrauerDipender Gill Stephen BurgessAgneta ÅkessonKarl MichaëlssonXue LiXia ShenSusanna C Larsson

Published in: medRxiv : the preprint server for health sciences (2023)

This genome-wide association study and trans-omic Mendelian randomization analysis provides insights into disease risk prediction, pathophysiology and downstream sequelae.

Keyphrases

genome wide association study
atrial fibrillation
heart failure
left atrial appendage
direct oral anticoagulants
dna methylation
oral anticoagulants
percutaneous coronary intervention
venous thromboembolism
left ventricular