The effect of vitamin D and zoledronic acid in bone marrow adiposity in kidney transplant patients: A post hoc analysis.

Mariel J HernandezLuciene M Dos ReisIgor D MarquesMaria J AraujoCesar A M TruytsIvone B OliveiraFellype C BarretoElias David-NetoMelani R CustodioRosa M MoysesEzequiel Bellorin-FontVanda Jorgetti

Published in: PloS one (2018)

In conclusion, the present study suggests that KT fails to normalize bone marrow adiposity, and it even gets worse with the use of ZA. Moreover, bone marrow adiposity is inversely associated with bone Volume and Turnover, which seems to be accentuated by the antiresorptive therapy.

Keyphrases

bone marrow
mesenchymal stem cells
insulin resistance
end stage renal disease
bone mineral density
newly diagnosed
chronic kidney disease
weight gain
ejection fraction
prognostic factors
peritoneal dialysis
type diabetes
patient reported outcomes
adipose tissue
metabolic syndrome
body mass index
physical activity