Optimizing Early-Stage Clinical Pharmacology Evaluation to Accelerate Clinical Development of Giredestrant in Advanced Breast Cancer.

Vikram Malhi Priya Agarwal Mary R Gates Lichuan Liu Jianshuang Wang Tom De Bruyn Scott Lam Jennifer Eng-Wong Pablo Perez-Moreno Ya-Chi Chen Jiajie Yu

Published in: Cancer research communications (2023)

This study illustrates how the integration of clinical pharmacology considerations into early-phase clinical trials can inform the design of pivotal studies and accelerate oncology drug development.

Keyphrases

early stage
clinical trial
palliative care
radiation therapy
young adults
lymph node
open label
case control