Draft Whole-Genome Sequences of Periodontal Pathobionts Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia Contain Phase-Variable Restriction-Modification Systems.

Richard D HaighLiam A CrawfordJoseph D RalphJoseph J WanfordSonia R VartoukianKarolin HijaziWilliam G WadeMarco R Oggioni

Published in: Genome announcements (2017)

Periodontal disease comprises mild to severe inflammatory host responses to oral bacteria that can cause destruction of the tooth-supporting tissue. We report genome sequences for 18 clinical isolates of Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia, Gram-negative obligate anaerobes that play a role in the periodontal disease process.

Keyphrases

gram negative
multidrug resistant
oxidative stress
early onset
genome wide
gene expression
drug induced