Porphyromonas gingivalis infection in the oral cavity is associated with elevated galactose-deficient IgA1 and increased nephritis severity in IgA nephropathy.
Seigo ItoTaro MisakiYasuyuki NagasawaRyota NomuraShuhei NakaAkiko FukunagaDaiki MatsuokaSaaya MatayoshiMichiyo Matsumoto-NakanoKazuhiko NakanoPublished in: Clinical and experimental nephrology (2023)
Our findings suggest an association between the presence of P. gingivalis in the oral cavity and the pathogenesis of IgAN, mediated by increased levels of Gd-IgA1.
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