Paeoniflorin combined with norfloxacin ameliorates drug-resistant Streptococcus suis infection.
Jinpeng LiQingying FanJing ZuoBingqian XueXiaoling ZhangYing WeiLiyun SunDaniel GrenierLi YiXiaogai HouYang WangPublished in: The Journal of antimicrobial chemotherapy (2022)
This study highlighted the inhibitory potential of paeoniflorin on the LuxS/AI-2 QS system of S. suis, and provided evidence that it can inhibit the FQ efflux pump and prevent biofilm formation to cooperate with norfloxacin in the treatment of resistant S. suis-related infections.