Genetic association between interleukin-10 gene rs1518111 and rs3021094 polymorphisms and risk of type 1 diabetes and diabetic nephropathy in Egyptian children and adolescents.

Rania Mostafa El HelalyRasha Rizk ElzeheryOla Ali El-EmamHuda Ahmed El DomiatyWesam Reda ElbohyHadil Mohamed AboeleninNanees Abdel-Badie Salem

Published in: Pediatric diabetes (2021)

AA genotype and A allele of IL-10 rs1518111 SNP could be linked to increased risk for T1DM and DN among Egyptian children. None of rs3021094 genotypes or alleles displayed significant association with DN. GA and AC haplotypes could be protective against T1DM and DN susceptibility.

Keyphrases

diabetic nephropathy
type diabetes
genome wide
glycemic control
copy number
pet ct
young adults
weight loss
transcription factor