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Among Other Tissues, Short-Term Garlic Oral Treatment Incrementally Improves Indicants of Only Pancreatic Islets of Langerhans Histology and Insulin mRNA Transcription and Synthesis in Diabetic Rats.

Amani M Al-AdsaniKhaled K Al-Qattan
Published in: Biology (2024)
8 weeks of garlic oral treatment is enough to incrementally restore only pancreatic islets of Langerhans insulin intensity and insulinogenic cells proliferation, morphology, and distribution. These indices were associated with enhanced pancreatic insulin mRNA transcription and synthesis. Eight weeks of garlic treatment were not enough to stimulate insulinogenesis in either the bile duct or the liver.
Keyphrases
  • type diabetes
  • diabetic rats
  • induced apoptosis
  • signaling pathway
  • gene expression
  • glycemic control
  • metabolic syndrome
  • cell proliferation
  • combination therapy
  • endoplasmic reticulum stress
  • cell cycle arrest
  • pi k akt