Effects of chronic treatment with botulinum toxin type A in salivary glands of rats: Histological and immunohistochemical analyses.
Luciana Silva RegueiraLiriane Baratella-EvêncioJaciel Benedito de OliveiraPriscilla Suelen Oliveira Carvalho da SilvaGabriela Andrade Lima ValençaJuliana Cristina Peixoto ConceiçãoDanyel Elias da Cruz PerezPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2019)
BoNT-A caused histological and cellular changes in submandibular-sublingual complex, followed by a tendency toward reversal after 35 days. The reversal characteristic of cellular changes in the submandibular-sublingual complex suggests that this BoNT-A formulation may be safely used for sialorrhea treatment.
Keyphrases