The Tale-Tell Heart: Evolutionary tetrapod shift from aquatic to terrestrial life-style reflected in heart changes in axolotl (Ambystoma mexicanum).

Veronika OlejnickovaHana KolesovaMartin BartosDavid Sedmera Martina Gregorovičová

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2021)

Transition from aquatic to terrestrial life-style is reflected in the heart morphology and function. Rebuilding of the axolotl heart during metamorphosis was connected with reorganization of ventricular trabeculae, completion of the atrial septum and its connection to the atrioventricular valve, and acceleration of AV conduction.

Keyphrases

heart failure
atrial fibrillation
risk assessment
catheter ablation
aortic valve
mitral valve
gene expression
genome wide
left atrial
dna methylation
coronary artery disease
aortic stenosis