The Clinical Utility of Genetic Testing in the Diagnosis and Management of Adults With Chronic Kidney Disease.

Neera K Dahl Michelle S BloomFouad T ChebibDinah ClarkMaggie Westemeyer Sara JandeskaZhiji ZhangHila Milo Rasouly Victoria Kolupaeva Maddalena MarasàVarshasb BroumandRichard A FaticaDominic S RajZachary P DemkoKyle MarshallSumit Punj Hossein Tabriziani Sangeeta M Bhorade Ali G Gharavi

Published in: Journal of the American Society of Nephrology : JASN (2023)

Genetic testing with a CKD-focused 385-gene panel substantially refined clinical diagnoses and had widespread implications for clinical management, including appropriate treatment strategies. These data support the utility of broader integration of panels of genetic tests into the clinical care paradigm for CKD patients.

Keyphrases

chronic kidney disease
end stage renal disease
peritoneal dialysis
genome wide
healthcare
ejection fraction
copy number
palliative care
newly diagnosed
prognostic factors
quality improvement
gene expression
big data
dna methylation
patient reported outcomes
chronic pain
pain management
deep learning