[Molecular genetic aspects of Fuchs' endothelial corneal dystrophy pathogenesis].

Published in: Vestnik oftalmologii (2020)

Fuchs' corneal dystrophy (FCD) is a common bilateral non-inflammatory endothelial pathology. It is a multigenic disorder with various expressivity, penetrance and population prevalence. This review discusses corneal endothelium pump function, FCD pathogenesis and its known genetic factors.

Keyphrases

optical coherence tomography
wound healing
endothelial cells
early onset
genome wide
cataract surgery
nitric oxide
oxidative stress
case report
gene expression