Context-dependent environmental associations with endometrial cancer histotype and genotype.

Sanaa Nakad Borrego Katherine C KurnitLaura Jane TurnerRussell R Broaddus

Published in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2023)

methylated endometrial cancer with age and body mass index is complex and somewhat dependent on tumor grade. As body mass index is modifiable, it is possible that weight loss induces a 'molecular switch' to alter the histologic characteristics of an endometrial cancer.

Keyphrases

endometrial cancer
body mass index
weight loss
weight gain
physical activity
bariatric surgery
roux en y gastric bypass
type diabetes
insulin resistance
single molecule
adipose tissue
climate change
skeletal muscle